BDBM102620 BMX-IN-1::N-[5-[9-[4-(methanesulfonamido)phenyl]-2-oxobenzo[h][1,::US10000483, Compound I-14

SMILES Cc1ccc(cc1NC(=O)C=C)-n1c2c(ccc1=O)cnc1ccc(cc21)-c1ccc(NS(C)(=O)=O)cc1

InChI Key InChIKey=SFMJNHNUOVADRW-UHFFFAOYSA-N

Data  1 KI  20 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 102620   

TargetTyrosine-protein kinase Blk(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM102620(BMX-IN-1 | N-[5-[9-[4-(methanesulfonamido)phenyl]-...)
Affinity DataIC50:  377nMAssay Description:DiscoverX binding assays were performed according to published methods (Fabian et al., Nat. Biotechnol. 23, 329-36 (2005); Davis et al., Nat. Biotech...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase Blk(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM102620(BMX-IN-1 | N-[5-[9-[4-(methanesulfonamido)phenyl]-...)
Affinity DataIC50:  377nMAssay Description:Inhibition of recombinant full length His-tagged human BLK expressed in baculovirus expression system using poly (4:1 Glu, Tyr) as substrate preincub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Blk(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM102620(BMX-IN-1 | N-[5-[9-[4-(methanesulfonamido)phenyl]-...)
Affinity DataIC50:  377nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed